Dremel drilling thicker glass is a long tedious process, go with the diamond drills, use plenty water for cooling and go slow, have a lot of patience. Rushing is not good.
[quote] I was going to drill the return lines 3" in from each side of the tank and about 3" from the top.[unquote]
I wouldnt do that, it adds 2 more holes to drill, increasing your chances of a mishap, and then you have 2 more drains back to the tank in a power off scenario, unless they come back into the overflow section and you use line-loc or something to go over the overflow wier and into the tank. IME better to have the returns go over the top, with siphon break holes. Its a lot more flexible , you can move the return hose around as needed
