Let's see. Connect the house tap water supply to an RO that direct feeds into the tank. Some kind of
float switch to cut RO water on and off as needed by tank. Float switch fails while you're at work and tank not only overflows into your house but the salinity goes to zero and kills all your fish and corals.
The only thing I have to lift is the salt buckets (and I finally talked the LFS into buying bags; cheaper and lighter.) I run my RO/DI into a reservoir from which I fill my topoff container. IF (rather when) float switch sticks worst that can happen is entire topoff container pumps into tank (5 gallon topoff into 150 tank, not much dilution)
Second container is for mixing salt water, salt dumped in and RO/DI water pumped from fresh water container.
Easy and safe.